TearScan IgE Allergy Test
Allergic Conjunctivitis IgE Assay
Ocular Immunoglobulin E (IgE) is a biomarker for allergic conjunctivitis, which often mimics dry eye disease or co-exists with dry eye disease.
What is Allergic Conjunctivitis?
Allergic conjunctivitis occurs when allergens (e.g., pollen, dust mites, or pet dander) trigger an immune response in the conjunctiva, the thin membrane covering the white of the eye and inner eyelids. The immune system produces allergen-specific IgE antibodies, which bind to mast cells in the conjunctiva. When allergens contact these IgE-bound mast cells, it causes degranulation, releasing histamine and other mediators. This leads to the characteristic symptoms of allergic conjunctivitis: redness, itching, swelling, and tearing. The process also increases local IgE levels in the conjunctival tissue, contributing to the inflammatory response.
Allergic conjunctivitis is increasingly prevalent as we experience longer allergy seasons but continues to be underdiagnosed due to the lack of rapid point-of-care diagnostic tools. Up to 40% of the U.S. population experiences symptoms of allergic conjunctivitis annually.
More severe acute presentations of allergic conjunctivitis are frequently challenging to differentiate from viral conjunctivitis.
The presence Allergic Conjunctivitis often masks and can accentuate the signs and symptoms of DED; thus it is important to assess the presence and amount of the biomarker IgE during an initial Dry Eye evaluation to aid the physician in determining if Allergic Conjunctivitis is present.
AXIM TearScan IgE
Total IgE in tear fluid increases with the severity of allergic response. Thus, determination of total tear IgE level is useful not only for making a clinical diagnosis of allergic conjunctivitis but also for the assessment of severity and the response to therapeutic intervention.
Total IgE in tear fluid increases with the severity of allergic response. Thus, determination of total tear IgE level is useful not only for making a clinical diagnosis of allergic conjunctivitis but also for the assessment of severity and the response to therapeutic intervention.
Results are available in less than 10 minutes, and give physicians the ability to test and treat patients suffering from allergic conjunctivitis.
More Information
Test time: 10 mins
Sample (size and type): 1.0 microliter in tears
Test results: Normal IgE: 40 ng/ml
Sensitivity: 93%
Specificity: 96%
Shelf life: 12 months
For more information and to order, contact us at hello@aximbiotech.com or +1 858 256-5132